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Product Literature

  • Product: Ponatinib

    Headline: Efficacy of ponatinib against ABL tyrosine kinase inhibitor-resistant leukemia cells

    Author: Seiichi Okabe, Tetsuzo Tauchi, Yuko Tanaka, Kazuma Ohyashiki

  • Product: TAE684, crizotinib & AZD6244

    Headline: Combined effect of ALK and MEK inhibitors in EML4–ALK-positive non-small-cell lung cancer cells

    Author: J Tanizaki, I Okamoto, K Takezawa, K Sakai, K Azuma, K Kuwata, H Yamaguchi, E Hatashita, K Nishio, P A Janne and K Nakagawa

  • Product: vandetanib

    Headline: Differential roles of trans-phosphorylated EGFR, HER2, HER3, and RET as heterodimerisation partners of MET in lung cancer with MET amplification

    Author: J Tanizaki, I Okamoto, K Sakai and K Nakagawa

  • Product: CCI779

    Headline: mTOR-targeted therapy: Differential perturbation to mitochondrial membrane potential and permeability transition pore plays a role in therapeutic response...
    Author: Jae Eun Kimb, Qun Hea, Yaqing Chena, Celine Shib, Ker Yua, b

  • Product: Perifosine

    Headline: Perifosine sensitizes UVB-induced apoptosis in skin cells: New implication of skin cancer prevention?

    Author: Chao Ji, Yan-li Yang, Zhi Yang, Ying Tu, Lei Cheng, Bin Chen, Ji-ping Xia, Wei-ling Sun, Zhong-lan Su, Li He, Zhi-gang Bi

  • Product: BEZ235 & AZD6244

    Headline: Antitumor Action of the MET Tyrosine Kinase Inhibitor Crizotinib (PF-02341066) in Gastric Cancer Positive for MET Amplification

    Author: Wataru Okamoto, Isamu Okamoto, Tokuzo Arao, Kiyoko Kuwata, Erina Hatashita, Haruka Yamaguchi, Kazuko Sakai, Kazuyoshi Yanagihara, Kazuto Nishio, and Kazuhiko Nakagawa

  • Product: TAE684

    Headline: Role of ERK-BIM and STAT3-Survivin Signaling Pathways in ALK Inhibitor–Induced Apoptosis in EML4-ALK–Positive Lung Cancer

    Author: Ken Takezawa, Isamu Okamoto, Kazuto Nishio, Pasi A. J?nne, and Kazuhiko Nakagawa

  • Product: Halofuginone

    Headline: Therapeutic effect of Halofuginone on ITP mice by regulating the differentiation of Th cell subsets

    Author: Chengqiang Jin, 1, Yanxia Jia, Chengying Jin, Haixin Dong, Panpan Cheng, Jianwei Zhou, Yu Wang, Biying Zheng, Fang Liu

  • Product: Sorafenib

    Headline: 1082-39, an analogue of sorafenib, inhibited human cancer cell growth more potently than sorafenib

    Author: Jia-Hui Chu, Cui-Rong Zhao, Zhi-Yu Song, Rui-Qi Wang, Yi-Zhuo Qin, Wen-Bao Li, Xian-Jun Qu

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    Product Category

    PI3K/Akt/mTOR
    Cell Cycle/Checkpoint
    Angiogenesis/Tyrosine Kinase
    Apoptosis Pathway
    PARP/BET
    Aurora/Ksp Pathway
    MAPK Pathway
    Hormone Pathay
    Integrase/CCR5
    Proteases/HSP90/HSP70 Pathway
    Wnt/Hedgehog/Notch Pathway
    Jak/Stat Pathway
    Ca/cAMP/Lipid Signaling Pathway
    Neuro Signaling Pathway
    TGF-beta/Smad Signaling Pathway
    GPCR Pathway
    Ion channel Pathway
    Cytochrome P450 Pathway
    Others Pathway
    Intermediate