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BCP0004 Gefitinib
Gefitinib was found to be a potent inhibitor of EGFR kinase.
BCP0016 AG-490
AG490 is a member of the tryphostin family of tyrosine kinase inhibitors.
BCP0030 BIBW2992
BIBW-2992 is a potent oral, irreversible combined EGFR/HER2 inhibitor.
BCP0031 BMS-599626(HCl)
BMS-599626,an orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
BCP0055 Erlotinib Hydrochloride
Erlotinib is an inhibitor of human Epidermal growth factor receptor (EGFR) tyrosine kinase (IC50 = 2 nM) and decreases EGFR autophosphorylation in tumor cells (IC50 = 20 nM).
BCP0066 Lapatinib Ditosylate
Lapatinib is a potent inhibitor of EGFR kinase (Ki = 3 nM), ErbB-2 kinase (Ki = 13 nM), ErbB-4 kinase (Ki = 347 nM).
BCP0093 PD153035 hydrochloride
PD153035 is a potent and specific inhibitor of EGFR with Ki and IC50 of 5.2 pM and 29 pM, respectively.
BCP0148 Neratinib(HKI272)
Neratinib is an orally available, irreversible tyrosine kinase inhibitor with IC50 of 59 nM and 92 nM for HER2 and EGFR, respectively.
BCP0151 Lapatinib
Lapatinib is a potent inhibitor of EGFR kinase (Ki = 3 nM), ErbB-2 kinase (Ki = 13 nM), ErbB-4 kinase (Ki = 347 nM).
BCP0159 Pelitinib(EKB-569)
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