Product Pathways
BCP0230 KU55933
KU-55933 is an ATP-competitive inhibitor.
BCP0543 CP466722
Specific ATM inhibitor,no inhibition of PI3K or PI3K-like protein kinases (PIKK) or Abl kinase in cells
BCP000600 NVP-LDE225
LDE225(NVP-LDE225) is a novel and specific, orally bioavailable Smo inhibitor with an IC50 of 11 nM.
BCP000631 KU-60019
KU-60019 is 10-fold more effective than KU-55933 at blocking radiation-induced phosphorylation of key ATM targets in human glioma cells.
BCP000919 VE-821
VE-821 was described as a potent and selective inhibitor of protein kinase ATR.
Purmorphamine demonstrates activation of the Hedgehog signaling pathway
BCP0006737 PF-5274857
PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively.
BCP0007551 CGK733
BCP0007837 BMS833923;BMS-833923
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