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Itacitinib Chemical Structure

Itacitinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP13794CAS No. :1334298-90-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1334298-90-6 Cat. No. BCP13794
Name Itacitinib
Synonyms INCB39110;INCB-39110;INCB 39110; INCB039110; INCB-039110; INCB 039110;
SMILES N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(C5CCN(C(C6=C(F)C(C(F)(F)F)=NC=C6)=O)CC5)C1
Chemical Name
Formula C26H23F4N9O M. Wt 553.51
Purity 98% Storage Store at 4-8°C
Description Itacitinib, also known as INCB39110 or INCB039110, is a potent JAK1 tyrosine kinase inhibitor, which is currently in Phase II trials for the treatment of rheumatoid arthritis, myelofibrosis, rheumatoid arthritis and plaque psoriasis. INCB039110 produced significant improvements in sPGA, demonstrating proof of concept in chronic plaque psoriasis.
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