Home   >  
Others Pathway
  • PI3K/Akt/mTOR
∨
  >  
Autophagy
  • mTOR
∨
  >   Rapamycin
Rapamycin Chemical Structure

Rapamycin

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01404CAS No. ：53123-88-9Purity：98%
chem_1Get Quotation Now
 Tel: 0086-13026320035   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
  • Publications Citing of Biochempartner's Rapamycin
Cancer Biol Ther. 2014 Jun 1; 15(6): 721–734. Oncotarget. 2016 Oct 11; 7(41): 67071–67086.
Med Sci Monit. 2017; 23: 801–808. Int J Biol Sci. 2022; 18(3): 1107–1119.
Front Oncol. 2020; 10: 1615. Oncotarget. 2016 May 3; 7(18): 25224–25240.
  • Chemical Properties&Biological Activity
CAS No. 53123-88-9 Cat. No. BCP01404
Name Rapamycin
Synonyms Sirolimus;Rapamune; AY 22989; AY22989; AY-22989; WY090217; WY-090217; WY 090217;
SMILES C[C@@H](C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(C[C@@H]([C@H](C)C[C@@H]1CC[C@@H](O)C(OC)C1)OC2=O)=O)=O)C[C@H](C)/C=C/C=C/C=C(C)/[C@@H](OC)C[C@H]3O[C@](C(C(N4[C@H]2CCCC4)=O)=O)(O)[C@H](C)CC3
Chemical Name
Formula C51H79NO13 M. Wt 914.18
Purity 98% Storage Store at 4-8°C
Description Rapamycin is a natural macrocyclic lactone produced by the bacterium Streptomyces hygroscopicus, with immunosuppressant properties. In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to generate an immunosuppressive complex that binds to and inhibits the activation of the mammalian Target Of Rapamycin (mTOR), a key regulatory kinase. This results in inhibition of T lymphocyte activation and proliferation that occurs in response to antigenic and cytokine (IL-2, IL-4, and IL-15) stimulation and inhibition of antibody production.
  • Quality Control&Technical Support
H-NMR HPLC
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:Rapamycin supplier,Rapamycin purchase,Rapamycin manufacturer,Rapamycin distributor,Rapamycin cost,Rapamycin buy,Rapamycin for sale

0086-13720134139