BQU57
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1637739-82-2 | Cat. No. | BCP16865 |
| Name | BQU57 | ||
| Synonyms | BQU-57;BQU 57; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C16H13F3N4O | M. Wt | 334.3 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: BQU57 inhibits Ral binding to its effector RalBP1, Ral-mediated cell spreading in murine fibroblasts and anchorage-independent growth of human cancer cell lines. in vivo: H2122 xenograft tumors are collected 3h after a single intraperitoneal injection BQU57 (10/20/50 mg/kg) and activation of Ral in the extracts is analyzed in RalBP1 pull-down assays. Both RalA and RalB are significantly inhibited by BQU57. By contrast, no inhibition of Ras and RhoA activity is observed. | ||
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