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Vismodegib Chemical Structure

Vismodegib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01715CAS No. ：879085-55-9Purity：98%
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  • Publications Citing of Biochempartner's Vismodegib
Cell Death Dis. 2019 Sep; 10(9): 626. Autophagy. 2015 Feb; 11(2): 355–372.
Acta Pharmacol Sin. 2019 Feb; 40(2): 257–267.
  • Chemical Properties&Biological Activity
CAS No. 879085-55-9 Cat. No. BCP01715
Name Vismodegib
Synonyms GDC-0449;GDC 0449;GDC0449; RG3616; RG 3616; RG-3616;
SMILES
Chemical Name
Formula C19H14Cl2N2O3S M. Wt 421.31
Purity 98% Storage Store at 4-8°C
Description Vismodegib, also known as GDC-0449 or RG3616, is a hedgehog antagonist, is also a n orally bioavailable small molecule with potential antineoplastic activity. Hedgehog antagonist GDC-0449 targets the Hedgehog signaling pathway, blocking the activities of the Hedgehog-ligand cell surface receptors PTCH and/or SMO and suppressing Hedgehog signaling.
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H-NMR LCMS
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