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SB216763 Chemical Structure

SB216763

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01764CAS No. :280744-09-4Purity:>95%
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  • Chemical Properties&Biological Activity
CAS No. 280744-09-4 Cat. No. BCP01764
Name SB216763
Synonyms SB-216763;SB 216763;
SMILES
Chemical Name
Formula C19H12Cl2N2O2 M. Wt 371.22
Purity >95% Storage Store at 4-8°C
Description SB 216763 is potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 9 nM for GSK-3α); competes with ATP. SB 216763 has minimal activity against 24 other protein kinases (IC50 > 10 μ M). Stimulates glycogen synthesis, gene transcription and is neuroprotective. SB 216763 also reduces pulmonary inflammation and fibrosis in a mouse model.
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