Sunitinib Malate New
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| CAS No. | 341031-54-7 | Cat. No. | BCP01768 |
| Related Products | 557795-19-4（Sunitinib） | ||
| Name | Sunitinib Malate | ||
| Synonyms | SU 11248 Malate;SU11248 Malate;SU-11248 Malate; | ||
| SMILES | CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)F)NC2=O)C.C(C(C(=O)O)O)C(=O)O | ||
| Chemical Name | |||
| Formula | C26H33FN4O7 | M. Wt | 532.56 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Sunitinib Malate is the orally bioavailable malate salt of an indolinone-based tyrosine kinase inhibitor with potential antineoplastic activity. Sunitinib blocks the tyrosine kinase activities of vascular endothelial growth factor receptor 2 (VEGFR2), platelet-derived growth factor receptor b (PDGFRb), and c-kit, thereby inhibiting angiogenesis and cell proliferation. This agent also inhibits the phosphorylation of Fms-related tyrosine kinase 3 (FLT3), another receptor tyrosine kinase expressed by some leukemic cells. | ||
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