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Tacrolimus Chemical Structure

Tacrolimus

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP01807CAS No. ：104987-11-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 104987-11-3 Cat. No. BCP01807
Name Tacrolimus
Synonyms FK 506;FK506;FK-506;Tsukubaenolide;
SMILES O=C([C@@](CCCC1)([H])N1C(C([C@@]2(O)[C@H](C)C[C@H](OC)[C@@](O2)([H])[C@@H](OC)C[C@@H](C)C/C(C)=C/[C@H]3CC=C)=O)=O)O[C@H](/C(C)=C/[C@H]4CC(OC)C(O)CC4)[C@H](C)[C@@H](O)CC3=O
Chemical Name
Formula C44H69NO12 M. Wt 804.02
Purity 98% Storage Store at 4-8°C
Description Tacrolimus, also known as FK-506, is an immunosuppressive drug used mainly after allogeneic organ transplant to reduce the activity of the patient's immune system and to lower the risk of organ rejection. It is also used in a topical preparation in the treatment of atopic dermatitis (eczema), severe refractory uveitis after bone marrow transplants, exacerbations of minimal change disease, TH2-mediated diseases such as Kimura's disease, and the skin condition vitiligo. FK-506 is a macrolide isolated from the fungus Streptomyces tsukubaensis.
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