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Lapatinib Ditosylate Chemical Structure

Lapatinib Ditosylate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01815CAS No. :388082-78-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 388082-78-8 Cat. No. BCP01815
Related Products 231277-92-2(Lapatinib) 388082-77-7(Lapatinib ditosylate)
Name Lapatinib Ditosylate
Synonyms Tykerb Ditosylate;GW572016 ditosylate; GW2016 ditosylate;
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.CC1=CC=C(C=C1)S(=O)(=O)O.CS(=O)(=O)CCNCC1=CC=C(O1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl
Chemical Name
Formula C29H26ClFN4O4S.2(C7H8O3S) M. Wt 925.46
Purity 98% Storage Store at 4-8°C
Description Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types.
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