Mirdametinib New
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Publications Citing of Biochempartner's Mirdametinib
| CAS No. | 391210-10-9 | Cat. No. | BCP01841 |
| Name | Mirdametinib | ||
| Synonyms | 870474-62-7;PD 0325901;PD325901;PD-0325901; | ||
| SMILES | C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOCC(CO)O | ||
| Chemical Name | |||
| Formula | C16H14F3IN2O4 | M. Wt | 482.19 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Mirdametinib is an orally bioavailable, synthetic organic molecule targeting mitogen-activated protein kinase kinase (MAPK/ERK kinase or MEK) with potential antineoplastic activity. Upon administration, mirdametinib selectively binds to and inhibits MEK, which may result in the inhibition of the phosphorylation and activation of MAPK/ERK and the inhibition of tumor cell proliferation. The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. | ||
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