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TRV130 hydrochloride Chemical Structure

TRV130 hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP19171CAS No. :1401031-39-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1401031-39-7 Cat. No. BCP19171
Name TRV130 hydrochloride
Synonyms TRV-130 hydrochloride;TRV 130 hydrochloride;
SMILES
Chemical Name
Formula C22H31ClN2O2S M. Wt 423.01
Purity 98% Storage Store at 4-8°C
Description in vitro: In cell-based assays, TRV130 elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less β-arrestin recruitment and receptor internalization . in vivo: In mice and rats, TRV130 is potently analgesic while causing less gastrointestinal dysfunction and respiratory suppression than morphine at equianalgesic doses . Compared to morphine, TRV130 (3, 4.5mg) elicited higher peak analgesia (105, 116 seconds latency vs 75 seconds for morphine, P
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