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DMXAA Chemical Structure

DMXAA

Data Sheet For research use only. Not for human use.
Cat. No. :BCP01949CAS No. :117570-53-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 117570-53-3 Cat. No. BCP01949
Name DMXAA
Synonyms ASA404; ASA 404; ASA-404; AS1404; AS 1404; AS-1404; Vadimezan;
SMILES
Chemical Name
Formula C17H14O4 M. Wt 282.29
Purity 98% Storage Store at 4-8°C
Description Combination of menadione and DMXAA leads to an increase in the antiproliferative activity of DLD-1 cells. DMXAA, as an antiviral agent, inhibits VSV-induced cytotoxicity and influenza virus replication in RAW 264.7 macrophages. A recent study shows that DMXAA has non-immune-mediated inhibitory effects against several kinase members of VEGFR (vascular endothelial growth factor receptor), such as VEGFR2 signalling in human umbilical vein endothelial cells.
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