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Telotristat ethyl Chemical Structure

Telotristat ethyl

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02293CAS No. :1033805-22-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1033805-22-9 Cat. No. BCP02293
Name Telotristat ethyl
Synonyms LX-1606;LX 1606;LX1606;
SMILES CCOC(=O)C(CC1=CC=C(C=C1)C2=CC(=NC(=N2)N)OC(C3=C(C=C(C=C3)Cl)N4C=CC(=N4)C)C(F)(F)F)N
Chemical Name
Formula C27H26ClF3N6O3 M. Wt 574.98
Purity 98% Storage Store at 4-8°C
Description Telotristat Ethyl is the ethyl ester form of telotristat, a tryptophan hydroxylase (TPH) inhibitor, with potential anti-serotonergic activity. Upon administration, telotristat binds to and inhibits the activity of TPH. This may result in a reduction in peripheral serotonin (5-HT) production and improvement of serotonin-mediated gastrointestinal effects such as severe diarrhea. TPH, the rate-limiting enzyme in serotonin biosynthesis, is overexpressed in carcinoid tumor cells.
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