Products

BCP02452's Information

CAS NO. 5142-23-4 structure
Product Name 3MA
Synonyms 3-MA; 3-methyl-adenin;3-Methyladenine;Adenine, 3-methyl-;3-Methyl-3H-purin-6-amine;3-Methyl-6-am; 6-Amino-3-methylpurine
Formula C6H7N5
Molecular Weight 149.15
Spec / Purity 98%
Supply Capacity can supply g scale
Product Description 3-Methyladenine (3-MA) is a specific inhibitor of PI3K activity and one of the most widely used inhibitors of the initial phase of the autophagic process: the sequestering of cytoplasmic material by the lysosome.
Details Autophagy Inhibitor, 3-MA is a synthetic intermediate and a cell-permeable autophagic sequestration blocker that protects cerebellar granule cells from apoptosis post serum/potassium deprivation. Autophagy Inhibitor, 3-MA is a class III PI 3-kinase inhibitor that displays distinctly different properties from the PI 3-kinase inhibitors LY 294002 and Wortmannin, in that treatment of cells with 3-MA results in specific redistribution of mannose 6-phosphate/insulin-like growth factor II receptor (MPR300), but does not cause the enlargement of late endosomal/lysosomal compartments.

Price Info Please inquire us for bulk quantity, thanks.
size Price Stock
5 G
---
Maintained in stock
1 G
US$317.90
Maintained in stock
100 MG
US$153.00
Maintained in stock

Quality Control
Batch No. File Type File Name
0000
DATASHEET
2014050501
LCMS
2014050501
NMR
2014052302
COA
2017021602
NMR
2017021602
LCMS

PI3K/Akt/mTOR
Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
PARP/BET
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Integrase/CCR5
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway
Intermediate