Home   >  
Cell Cycle/DNA Damage
  >  
CDK
  >   PHA-767491
PHA-767491 Chemical Structure

PHA-767491

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02855CAS No. :845714-00-3Purity:98%
 Tel: 0086-13026320035   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

 

* Applicant name

Catalog Number

 

* Institution/Company

* Email address

 

Phone number

Country

 

* Quantity Required

Remarks

  • Chemical Properties&Biological Activity
CAS No. 845714-00-3 Cat. No. BCP02855
Name PHA-767491
Synonyms PHA 767491;PHA767491;CAY-10572;CAY10572;CAY 10572;
SMILES
Chemical Name
Formula C12H11N3O M. Wt 213.24
Purity 98% Storage Store at 4-8°C
Description Cdc7 kinase is known to promote the activity of DNA replication origins in eukaryotic organisms. Inhibition of Cdc7 kinase causes blockade of DNA synthesis in human cell lines. Tumor cells are then funneled into the apoptotic pathway in a p53-independent manner. Pharmacological inhibition of Cdc7 kinase can be an effective strategy for the development of oncologic therapeutics useful for treatment of cancers. At 10 ?M, PHA-767491 induces apoptotic cell death in multiple cancer cell types. PHA-767491 also inhibits Cdk9, a kinase involved in the phosphorylation of RNA polymerase II and in transcriptional regulation of gene expression.
  • Quality Control&Technical Support
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:PHA-767491 supplier,PHA-767491 purchase,PHA-767491 manufacturer,PHA-767491 distributor,PHA-767491 cost,PHA-767491 buy,PHA-767491 for sale

0086-13720134139