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Tetrandrine Chemical Structure

Tetrandrine

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP02934CAS No. ：518-34-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 518-34-3 Cat. No. BCP02934
Name Tetrandrine
Synonyms Hanfangchin A;NSC 77037;Fanchinine;S,S-(+)-Tetrandrine;Sinomenine A;TTD;Tetrandrin;d-Tetrandr;
SMILES
Chemical Name
Formula C38H42N2O6 M. Wt 622.75
Purity 98% Storage Store at 4-8°C
Description Tetrandrine inhibits voltage-gated Ca2+ currents with an IC50 of 10.1 mM in isolated nerve terminals of the rat neurohypophysis. Tetrandrine is a high-affinity blocker of the type II, maxi-Ca(2+)-activated K+ channel of the rat neurohypophysial terminals with an IC50 of 0.21 mM. Another study shows that Tetrandrine also inhibits Ca(2+)-activated Cl- currents (I(Cl,Ca)) with an IC50 of 5.2 mM. Tetrandrine inhibits the proliferation of human leukemic HL-60 cells via induction of apoptosis.
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