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CK1827452 Chemical Structure

CK1827452

Data Sheet For research use only. Not for human use.
Cat. No. :BCP03048CAS No. :873697-71-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 873697-71-3 Cat. No. BCP03048
Name CK1827452
Synonyms Omecamtiv Mecarbil;CK-1827452;CK 1827452;
SMILES O=C(N1CCN(CC1)CC2=C(C(NC(NC3=CC=C(N=C3)C)=O)=CC=C2)F)OC
Chemical Name
Formula C20H24FN5O3 M. Wt 401.43
Purity 98% Storage Store at 4-8°C
Description Omecamtiv mecarbil, also known as CK-1827452, is a cardiac specific myosin activator. It is clinically tested for its role in the treatment of left ventricular systolic heart failure. Omecamtiv Mecarbil specifically targets and activates myocardial ATPase and improves energy utilization. Omecamtiv Mecarbil improves systolic function by increasing the systolic ejection duration/stroke volume, without consuming more ATP energy, oxygen or altering intracellular calcium levels causing an overall improvement in cardiac efficiency.
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