Actinomycin D
Data Sheet
For research use only. Not for human use.
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| CAS No. | 50-76-0 | Cat. No. | BCP04082 |
| Name | Actinomycin D | ||
| Synonyms | |||
| SMILES | |||
| Chemical Name | |||
| Formula | C62H86N12O16 | M. Wt | 1255.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Actinomycin D showed a concentration-dependent decrease of DNA repair activity with the IC50 of 0.42 μM. Actinomycin D (dactinomycin), a member of actinomycines, which are a class of polypeptide antibiotics isolated from soil bacteria of the genus Streptomyces. Have been used for many years as an older chemotherapy, actinomycin D binds to double- and single-stranded DNA to inhibit DNA and RNA synthesis by binding DNA at the transcription initiation complex and preventing elongation of RNA chain by RNA polymerase. | ||
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