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Fosaprepitant dimeglumine Chemical Structure

Fosaprepitant dimeglumine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP05167CAS No. :265121-04-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 265121-04-8 Cat. No. BCP05167
Related Products 172673-20-0(Fosaprepitant)
Name Fosaprepitant dimeglumine
Synonyms MK-0517 dimeglumine; MK0517 dimeglumine; MK 0517 dimeglumine;
SMILES CC(C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)OC2C(N(CCO2)CC3=NC(=O)N(N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNCC(C(C(C(CO)O)O)O)O.CNCC(C(C(C(CO)O)O)O)O
Chemical Name
Formula C23H22F7N4O6P·2C7H17NO5 M. Wt 1004.84
Purity 98% Storage Store at 4-8°C
Description Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
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