Parocoxib
Data Sheet
For research use only. Not for human use.
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| CAS No. | 198470-84-7 | Cat. No. | BCP07254 |
| Name | Parocoxib | ||
| Synonyms | SC69124;SC-69124;SC 69124; Valus-P; Vorth-P; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C19H18N2O4S | M. Wt | 370.42 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: The prodrug Parecoxib as well as its active metabolite val have a specific affinity to the cannabinoid (CB) receptor measured in CB1-expressing HEK 293 cells and rat brain tissue. in vivo: Adult male Sprague-Dawley rats were administered parecoxib (10 or 30 mg kg(-1), IP) or isotonic saline twice a day starting 24 h after middle cerebral artery occlusion (MCAO) for three consecutive days . The selective COX-2 inhibitor parecoxib was delivered 20 min before or 20 min after the incision by intraperitoneal injection. Pretreatment with parecoxib markedly attenuated the pain hypersensitivity induced by incision . | ||
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