RVX-208 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1044870-39-4 | Cat. No. | BCP07787 |
| Name | RVX-208 | ||
| Synonyms | RVX-000222; RVX000222; RVX 000222; RVX 208; RVX208;Apabetalone; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C20H22N2O5 | M. Wt | 370.4 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | RVX-208 is a first-in-class, small molecule that inhibits BET bromodomains. RVX-208 binds to the BET protein, it triggers a cascade of events leading to increased ApoA-I gene transcription and eventually production of the protein. RVX-208 increases apoA-I and HDL-C in vitro and in vivo. In AGMs, RVX-208 raises serum pre-beta(1)-LpA-I and alpha-LpA-I levels and enhances cholesterol efflux. RVX-208 is currently in phase II clinical trials. | ||
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