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(-)-Huperzine A Chemical Structure

(-)-Huperzine A

Data Sheet For research use only. Not for human use.
Cat. No. :BCP08891CAS No. :102518-79-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 102518-79-6 Cat. No. BCP08891
Name (-)-Huperzine A
Synonyms (-)-Selagine;
SMILES
Chemical Name
Formula C15H18N2O M. Wt 242.32
Purity 98% Storage Store at 4-8°C
Description (-)-Huperzine A is the more potent stereoisomer of racemic (±)-Huperzine A (sc-218582) preparations, an approximately 38-fold more potent inhibitor of AChE than (+)-Huperzine A. Both the (-) and (+) stereoisomers also demonstrate NMDA receptor antagonism with similar affinity. Pretreatment of cerebral neuronal cells with (-)-Huperzine A confers protection against glutamate-mediated Ca2+ influx and excitotoxicity, moderated by blockade of NMDA-associated ion channel activity.
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