Products

Cas No.Product NameDescription
57852-57-0Idarubicin hydrochlorideIdarubicin hydrochloride is a hydrochloride salt form of Idarubicin which is an anthracycline antibiotic and a DNA topoisomerase II inhibitor for MCF-7 cells with an IC50 of 3.3 ng/mL.
136572-09-3Irinotecan HCl TrihydrateThe anticancer agent, Irinotecan, is a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.
25316-40-9Doxorubicin HClDoxorubicin (Adriamycin) is an antibiotic agent that inhibits DNA topoisomerase II and induces DNA damage and apoptosis.
7689-03-4CamptothecinCamptothecin is a potent DNA enzyme topoisomerase I inhibitor with an IC50 and IC70 of 50 nM and 0.225 μM for breast cancer cell line MDA-MB-231.
56390-09-1Epirubicin Hydrochloride Epirubicin Hydrochloride is a cell-permeable antitumor antibiotic.
33419-42-0EtoposideEtoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA.
97682-44-5IrinotecanThe anticancer agent, Irinotecan, is a prodrug that is converted by tissue carboxylesterase to 7-ethyl-10-hydroxycamptothecin (SN-38), a potent inhibitor of DNA topoisomerase I.
65271-80-9MitoxantroneMitoxantrone, a type II topoisomerase inhibitor, is an anthracenedione-derived antineoplastic agent.
186826-86-8 Moxifloxacine hydrochlorideMoxifloxacin (Hydrochloride) is a synthetic fluoroquinolone antibiotic agent.
6559-91-74'-Demethylepipodophyllotoxin4'-demethylepipodophyllotoxin is a key intermediate compounds for the preparation of podophyllotoxin-type anti-cancer drugs.
117091-64-2Etoposide phosphateEtoposide Phosphate is a derivative of Etoposide (VP-16).
935888-69-0Oprozomib ONX-0912 (as known as oprozomib), is an orally bio-available and potent proteasome inhibitor that inhibits growth and induces apoptosis in bortezomib resistant multiple myeloma (MM) cells.
172889-26-8PP1PP1(AGL1872) is a Src family kinase,inhibitor.
256411-32-2CKD-602CKD-602, a topoisomerase I inhibitor.
1333151-73-7KPT-185KPT-185 is a selective CRM1 inhibitor.
354813-19-7BalicatibBalicatib, an inhibitor of the osteoclastic enzyme cathepsin K.
1332708-14-1PF-4840154PF-4840154 is a potent, selective agonist of the rat and human TrpA1 channel and elicited TrpA1-mediated nocifensive behaviour in mouse, with EC50 of 97 nM and 23 nM for rTrpA1 and hTrpA1, respectively.
78186-34-2BisantreneBisantrene is a highly effective antitumor drug, targets eukaryotic type II topoisomerases.

First Previous Next End   Jump to  Page
PI3K/Akt/mTOR
Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
PARP/BET
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Integrase/CCR5
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway
Intermediate