Products

Cas No.Product NameDescription
957118-49-9MK 3207MK-3207 is a potent and orally bioavailable CGRP receptor antagonist. In common with other CGRP receptor antagonists, MK-3207 displays lower affinity for human CGRP receptors from other species, including canine and rodent.
1246086-78-1VU 0364439Positive allosteric modulator (PAM) of mGlu4 receptors (EC50 = 19.8 nM in vitro for human mGlu4).
753498-25-8Indacaterol MaleateIndacaterol Maleate is an ultra-long-acting β-adrenoceptor agonist.
1186195-62-9IKK 16IKK 16 is a selective IκB kinase (IKK) inhibitor.
1373423-53-0GSK-J4GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3 and UTX with IC50 of 60 nM and inactive against a panel of demethylases of the JMJ family.
1374828-69-9GNE-0877GNE0877 is a highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitor with an IC50 of 3 nM.
266359-83-5ReparixinReparixin(DF 1681Y) is an inhibitor of CXCL8 receptor, also inhibit CXCR1 and CXCR2 activation, which has been shown to attenuate inflammatory responses in various injury models.
919351-41-0AZD1283AZD1283 is a potent antagonist of the P2Y12 receptor with EC50 of 3.0 ug/kg/min, TI >10; with binding IC50 of 11 nM.
1802326-66-4 JNJ 63533054JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM.
406205-74-1BAY 59-3074Bay 59-3074 is a novel, selective CB1/CB2 receptor partial agonist with Ki values of 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively .

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PI3K/Akt/mTOR
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Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
PARP/BET
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Integrase/CCR5
Proteases/HSP90/HSP70 Pathway
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Intermediate