Cas No.Product NameDescription
244218-51-7JTC-801 HClJTC-801 is a novel high affinity, selective opioid receptor-like1 receptor antagonist with a Ki of 8.2 nM.
1028969-49-4MCOPPB trihydrochlorideMCOPPB trihydrochloride is a high affinity NOP receptor (KOR-3) agonist.
156053-89-3AlvimopanAlvimopan(ADL 8-2698; Entereg; LY 246736) is a selective and competitive antagonist at mu-opioid receptors, found in myenteric and submucosal neurons and the immune cells of the lamina propria in the human gut.
357-08-4Naloxone HCl IC50 Value: 3nM(antagonized ACTH stimulation of cortisol release)[5] Naloxone hydrochloride is a widely used opioid antagonist.
16590-41-3NaltrexoneNaltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.
868273-06-7 Org 27569Potent CB1 receptor allosteric modulator (pEC50 = 8.24).
16676-29-2Naltrexone hydrochloride Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence
58895-64-0Nalmefene hydrochlorideOpioid receptor antagonist; displays a longer half life than Naloxone.
863513-91-1CebranopadolCebranopadol and GRT 6006 are novel first-in-class compounds with unique pharmacological and pharmacokinetic profiles that may enhance their effect in certain pain conditions.
522650-83-5SW-044248SW044248 is a novel noncanonical Top1 inhibitor with a pattern of selective toxicity for NSCLC cells.
1108147-88-1MCOPPB triHydrochlorideMCOPPB 3Hcl is a nociceptin receptor agonist with pKi of 10.07; weaker activity at other opioid receptors.
1401031-39-7TRV130 hydrochlorideTRV 130 Hcl is a novel μ-opioid receptor (MOR) G protein-biased ligand; elicits robust G protein signaling(pEC50=8.1), with potency and efficacy similar to morphine, but with far less β-arrestin recruitment and receptor internalization.

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Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway