Products

Cas No.Product NameDescription
775304-57-9TranslarnaPTC124 is CFTR-G542X nonsense allele inhibitor.
603139-19-1OdanacatibOdanacatib (MK 0822) is an inhibitor of cathepsin K with potential anti-osteoporotic activity.
355025-24-0Ki16425Ki16425 is a LPA receptor inhibitor with selectivity for LPA1 (Ki = 0.34μM)and LPA3(Ki = 0.93μM)vs.
504433-23-2GW441756GW441756 is a potent, selective inhibitor of TrkA with IC50 of 2 nM, with very little activity to c-Raf1 and CDK2.
211513-37-0DalcetrapibDalcetrapib is a CETP inhibitor for rhCETP with IC50 of 0.2 μM.
212844-54-7Purvalanol BPurvalanol B has been shown to be a cyclin-dependent kinase inhibitor.
623142-96-1Ki20227(+/-)Ki20227 is a c-Fms tyrosine kinase inhibitor.
91832-40-5CefdinirCefdinir (Omnicef) is a semi-synthetic, broad-spectrum antibiotic, which is proved to be effective for common bacterial infections of the ear, sinus, throat, and skin.
155270-99-8IstradefyllineIstradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist in experimental models of Parkinson's disease.
952021-60-2PF-477736PF 477736 is a CHK inhitor with Ki values of 0.49 and 47 nM for Chk1 and Chk2 respectively.
104054-27-5AtipamezoleAtipamezole is a synthetic alpha2-adrenergic antagonist.
1033805-22-9LX1606LX1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity.
166518-60-1AvasimibeAvasimibe at concentration of 1μg/mL causes reduction of Total cholesterol and Esterified cholesterol through inhibiting LDL binding and decreasing scavenger receptor numbers during foam cell formation in human monocyte-derived macrophages.
288150-92-5SB408124SB-408124 (SB 408124)is a selective non-peptide orexin OX1 receptor antagonist .
344458-15-7PJ 34 HClPJ34 HCl is the hydrochloride salt of PJ34, which is a PARP inhibitor with EC50 of 20 nM and is equally potent to PARP1/2.
154992-24-2RU58841 RU 58841 has a dramatic effect on hair regrowth.
875446-37-0AnacetrapibAnacetrapib is a CETP (Cholesteryl ester transfer protein) inhibitor developed to treat high cholesterol levels and prevent cardiovascular disease.
82964-04-3TolrestatTolrestat(AY-27773) is a potent, orally active aldose reductase inhibitor with IC50 value of 35 nM.
168021-79-2NXY-059NXY-059 is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone.
1283519-40-3KN-92KN-92 is the inactive form of KN-93.

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PI3K/Akt/mTOR
Cell Cycle/Checkpoint
Angiogenesis/Tyrosine Kinase
Apoptosis Pathway
PARP/BET
Aurora/Ksp Pathway
MAPK Pathway
Hormone Pathay
Integrase/CCR5
Proteases/HSP90/HSP70 Pathway
Wnt/Hedgehog/Notch Pathway
Jak/Stat Pathway
Ca/cAMP/Lipid Signaling Pathway
Neuro Signaling Pathway
TGF-beta/Smad Signaling Pathway
GPCR Pathway
Ion channel Pathway
Cytochrome P450 Pathway
Others Pathway
Intermediate