Bisindoylmaleimide X HCl

  • Chemical Properties
CAS No. 145317-11-9 Cat. No. BCP25394
Name Bisindoylmaleimide X HCl
Synonyms Bisindolylmaleimide X hydrochloride;BIM-X hydrochloride; Ro31-8425 hydrochloride;
Formula C26H24N4O2.HCl M. Wt 460.96
  • Biological Activity
Description Bisindolylmaleimide X hydrochloride is a potent and selective protein kinase C (PKC) inhibitor. Bisindolylmaleimide X hydrochloride is a potent cyclin-dependent kinase 2 (CDK2) antagonist with an IC50 of 200 nM.
Pathways TGF beta/Smad  Epigenetics 
Targets PKC 

Structure

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