SB 203580 hydrochloride
| CAS No. | 869185-85-3 | Cat. No. | BCP29070 |
| Name | SB 203580 hydrochloride | ||
| Synonyms | RWJ 64809 hydrochloride;RWJ64809 HCl;SB203580 HCl; | ||
| Formula | C21H17ClFN3OS | M. Wt | 413.9 |
| Description | SB 203580 hydrochloride is a water-soluble form of the potent MAP kinase inhibitor SB 203580 with IC50 values of 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2, respectively. It was shown to inhibit interleukin-2-induced T cell proliferation, cyclooxygenase-1 and -2, and thromboxane synthase. | ||
| Pathways | MAPK Pathway | ||
| Targets | p38 MAPK | ||
Structure
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