VP3.15
| CAS No. | 1281681-54-6 | Cat. No. | BCP31223 |
| Name | VP3.15 | ||
| Synonyms | VP-3.15; | ||
| Formula | C20H22N4OS | M. Wt | 366.48 |
| Description | VP3.15 is a potent, orally bioavailable and CNS-penetrant dual phosphodiesterase (PDE)7- glycogen synthase kinase (GSK)3 inhibitor, with IC50s of 1.59 μM and 0.88 μM for PDE7 and GSK-3, respectively. VP3.15 has neuroprotective and neuroreparative activities, thus as potential combined anti-inflammatory and pro-remyelinating therapies for multiple sclerosis (MS). | ||
| Pathways | Protease/Metabolic Enzyme Wnt/Stem Cell PI3K/Akt/mTOR | ||
| Targets | Phosphodiesterase/PDE GSK3 | ||
Structure
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