INT-777

  • Chemical Properties
CAS No. 1199796-29-6 Cat. No. BCP33245
Name INT-777
Synonyms INT 777; INT777; 6-EMCA; S-EMCA;
Formula C27H46O5 M. Wt 450.65
  • Biological Activity
Description INT-777 is a semisynthetic bile acid that acts as an agonist of TGR5 (EC50 = 0.82 µM). INT-777 mitigates inflammatory response in human endometriotic stromal cells: A therapeutic implication for endometriosis.
Pathways GPCR/G Protein 

Structure

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