Melphalan Hydrochloride
| CAS No. | 3223-07-2 | Cat. No. | BCP33593 |
| Name | Melphalan Hydrochloride | ||
| Synonyms | Melphalan HCl;L-Sarcolysine hydrochloride;CB 3025 hydrochloride; | ||
| Formula | C13H19Cl3N2O2 | M. Wt | 341.66 |
| Description | Melphalan Hydrochloride is a bifunctional alkylating agent and phenylalanine derivative of nitrogen mustard. Melphalan hydrochloride is converted into highly reactive ethylenimmonium intermediates that induce covalent guanine N7-N7 intra- and inter-crosslinks and alkylation of adenine N3 of DNA. This agent also alkylates RNA and protein structures. As a result RNA transcription and protein synthesis are inhibited, ultimately leading to cell growth arrest and/or death. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | DNA Alkylator/Crosslinker | ||
Structure
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