Calpeptin

  • Chemical Properties
CAS No. 117591-20-5 Cat. No. BCP34012
Name Calpeptin
Synonyms N-Cbz-leu-nleu-al;Benzylcarbonyl-leu-nleu-H;
Formula C20H30N2O4 M. Wt 362.46
  • Biological Activity
Description Calpeptin is a rho kinase activator and an inhibitor of calpains, a family of calcium-dependent cysteine proteases involved in apoptosis, long-term potentiation in neurons, and cell cycle progression. Calpeptin attenuates apoptosis and inflammation, cell death, and axonal damage in animal model of multiple sclerosis. Calpeptin provides functional neuroprotection to rat retinal ganglion cells following Ca2+ influx.
Pathways Protease/Metabolic Enzyme 
Targets Cathepsin 

Structure

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