BMP signaling agonist sb4

  • Chemical Properties
CAS No. 100874-08-6 Cat. No. BCP37563
Name BMP signaling agonist sb4
Synonyms SB 4; SB4; SB-4; SB-4 agonist;
Formula C14H10BrNOS M. Wt 320.20
  • Biological Activity
Description BMP signaling agonist sb4 is a potent benzoxazole bone morphogenetic protein 4 (BMP4) signaling agonist with a EC50 value of 74 nM, activates BMP signaling by stabilizing intracellular p-SMAD-1/5/9. BMP signaling agonist sb4 activates BMP4 target genes (inhibitors of DNA binding, Id1 and Id3) canonical BMP signaling.
Pathways TGF beta/Smad  
Targets BMP/TGF beta Receptor 

Structure

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