Amcenestrant
| CAS No. | 2114339-57-8 | Cat. No. | BCP38455 |
| Name | Amcenestrant | ||
| Synonyms | SAR439859; SAR-439859; SAR 439859; | ||
| Formula | C31H30Cl2FNO3 | M. Wt | 554.48 |
| Description | Amcenestrant, also known as SAR439859, is an orally available, nonsteroidal selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD SAR439859 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation. This prevents ER-mediated signaling and inhibits both the growth and survival of ER-expressing cancer cells | ||
| Pathways | Hormone Pathay | ||
| Targets | Estrogen Receptor | ||
Structure
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