KEA1-97

  • Chemical Properties
CAS No. 2138882-71-8 Cat. No. BCP42477
Name KEA1-97
Synonyms KEA1 97; KEA197;KEA 1-97;
Formula C15H9Cl2FN4 M. Wt 335.16
  • Biological Activity
Description KEA1-97 is a thioredoxin-caspase 3 interaction disruptor. It has been shown to impair breast cancer pathogenicity. KEA1-97 disrupts the interaction of thioredoxin with caspase 3, activates caspases, and induces apoptosis without affecting thioredoxin activity. Moreover, KEA1-97 impairs in vivo breast tumor xenograft growth.
Pathways Protease/Metabolic Enzyme Apoptosis Pathway 
Targets Caspase 

Structure

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