Venadaparib
| CAS No. | 1681017-83-3 | Cat. No. | BCP42946 |
| Name | Venadaparib | ||
| Synonyms | IDX-1197;IDX 1197;IDX1197; | ||
| Formula | C23H23FN4O2 | M. Wt | 406.46 |
| Description | Venadaparib is a potent, selective and orally active PARP inhibitor with IC50s of 1.4 nM and 1.0 nM for PARP1 and PARP2, respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research. | ||
| Pathways | Cell Cycle/DNA Damage Epigenetics | ||
| Targets | PARP | ||
Structure
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