SB-747651A
| CAS No. | 607372-46-3 | Cat. No. | BCP46274 |
| Name | SB-747651A | ||
| Synonyms | SB 747651A; SB747651A;SB-747651-A; | ||
| Formula | C16H22N8O | M. Wt | 342.41 |
| Description | SB-747651A is a potent, ATP-competitive mitogen- and stress-activated kinase 1 (MSK1) inhibitor (IC50 = 11 nM in an in vitro kinase assay). It targets the N-terminal kinase domain. SB-747651A inhibits MSK1, MSK2, PKA, PKB, RSK and p70S6K activity in cells. | ||
| Related Products | 1781882-72-1（SB-747651A dihydrochloride） | ||
| Pathways | MAPK Pathway | ||
| Targets | p38 MAPK | ||
Structure
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