VU0467154

  • Chemical Properties
CAS No. 1451993-15-9 Cat. No. BCP47001
Name VU0467154
Synonyms VU-0467154;VU 0467154;
Formula C17H15F3N4O3S2 M. Wt 444.45
  • Biological Activity
Description VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor. It potentiates acetylcholine responses in CHO cells expressing M4 receptors (EC50s = 17.7, 630, and 1,000 nM for rat, human, and cynomolgus monkey receptors, respectively).
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets mAChR 

Structure

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