Z-LLY-FMK

  • Chemical Properties
CAS No. 133410-84-1 Cat. No. BCP48122
Name Z-LLY-FMK
Synonyms Calpain Inhibitor IV;Z-Leu-Leu-Tyr-Fluoromethylketone;Z-Leu-Leu-Tyr-FMK;
Formula C30H40FN3O6 M. Wt 557.65
  • Biological Activity
Description Z-LLY-FMK is a cell-permeant and irreversible calpain inhibitor that is selective for calpain II, and also exhibits inhibitory effect against cathepsin L. It was shown to suppress hepatocyte apoptosis after bile duct ligation in rat.
Pathways Protease/Metabolic Enzyme 
Targets Proteasome 

Structure

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