Filgotinib maleate

  • Chemical Properties
CAS No. 1802998-75-9 Cat. No. BCP49095
Name Filgotinib maleate
Synonyms GS 6034 maleate; GS6034 maleate; GS-6034 maleate;
Formula C25H27N5O7S M. Wt 541.58
  • Biological Activity
Description Filgotinib (maleate) is a selective and orally active JAK1 inhibitor with IC50 of 10 nM, 28 nM, 810 nM and 116 nM for JAK1, JAK2, JAK3 and TYK2, respectively. Filgotinib (maleate) can be used for rheumatoid arthritis (RA) and Crohn's disease research.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway Wnt/Stem Cell Epigenetics 
Targets JAK 

Structure

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