Cilostamide
| CAS No. | 68550-75-4 | Cat. No. | BCP08355 |
| Name | Cilostamide | ||
| Synonyms | OPC3689;OPC 3689;OPC-3689; | ||
| Formula | C20H26N2O3 | M. Wt | 342.44 |
| Description | Selective inhibitor of type III phosphodiesterase (PDE3). Displays moderate selectivity for PDE3A isozyme vs. PDE3B (IC50 values are 0.027 and 0.050 μM for PDE3A and PDE3B respectively). Inhibits ADP-induced platelet aggregation (IC50 = 16.8 μM); antithrombotic. Also available as part of the Phosphodiesterase Inhibitor Tocrise. | ||
| Pathways | Protease/Metabolic Enzyme | ||
| Targets | Phosphodiesterase/PDE | ||
Structure
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