Rigosertib sodium

  • Chemical Properties
CAS No. 592542-60-4 Cat. No. BCP08297
Name Rigosertib sodium
Synonyms ON-01910 sodium; ON 01910 sodium; ON01910 sodium;
Formula C21H24NO8S. Na M. Wt 473.47
  • Biological Activity
Description Rigosertib (ON-01910) is a non-ATP-competitive inhibitor of PLK1 with IC50 of 9 nM. It shows 30-fold greater selectivity against Plk2 and no activity to Plk3.
Pathways Cell Cycle/DNA Damage 
Targets PLK 

Structure

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