DBeQ

  • Chemical Properties
CAS No. 177355-84-9 Cat. No. BCP07830
Name DBeQ
Synonyms
Formula C22H20N4 M. Wt 340.42
  • Biological Activity
Description Selective and reversible inhibitor of p97 ATPase (IC50 = 1.5 μM). Induces executioner caspases (caspase-3 and caspase-7) rapidly. Blocks the degradation of endoplasmic reticulum-associated degradation (ERAD) reporters; also blocks autophagosome maturation and promotes accumulation of LC3-II.
Pathways Ion Channel/Membrane Transporter Cell Cycle/DNA Damage 
Targets ATPase p97 

Structure

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