SMI-4a
| CAS No. | 327033-36-3 | Cat. No. | BCP21212 |
| Name | SMI-4a | ||
| Synonyms | SMI4a; SMI 4a; TCS-PIM-1-4a; | ||
| Formula | C11H6F3NO2S | M. Wt | 273.23 |
| Description | SMI-4a, also called as TCS-PIM-1-4a, a thiazolidinedione compound, is a potent, selective ATP-competitive inhibitor against Pim protein kinase (IC50 = 24 nM against Pim-1 and 100 nM against Pim-2) with little or no activity against a panel of 58 other kinase. | ||
| Pathways | Jak/Stat Pathway | ||
| Targets | Pim | ||
Structure
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