Fosaprepitant dimeglumine
| CAS No. | 265121-04-8 | Cat. No. | BCP05167 |
| Name | Fosaprepitant dimeglumine | ||
| Synonyms | MK-0517 dimeglumine; MK0517 dimeglumine; MK 0517 dimeglumine; | ||
| Formula | C23H22F7N4O6P·2C7H17NO5 | M. Wt | 1004.84 |
| Description | Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis. | ||
| Related Products | 172673-20-0（Fosaprepitant） | ||
| Pathways | GPCR/G Protein | ||
| Targets | NK Receptor | ||
Structure
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