LY2874455

  • Chemical Properties
CAS No. 1254473-64-7 Cat. No. BCP04756
Name LY2874455
Synonyms LY 2874455;LY-2874455;
Formula C21H19Cl2N5O2 M. Wt 444.31
  • Biological Activity
Description LY2874455 exhibits a potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activity in several tumor xenograft models representing the major FGF/FGFR relevant tumor histologies including lung, gastric, and bladder cancers and multiple myeloma, and with a well-defined pharmacokinetic/pharmacodynamic relationship.
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets FGFR 

Structure

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