Ciproxifan maleate

  • Chemical Properties
CAS No. 184025-19-2 Cat. No. BCP04664
Name Ciproxifan maleate
Synonyms FUB 359 maleate;FUB359 maleate;FUB-359 maleate;
Formula C16H18N2O2.C4H4O4 M. Wt 386.4
  • Biological Activity
Description Ciproxifan is an extremely potent histamine H3 inverse agonist/antagonist.Ciproxifan produces wakefulness and attentiveness in animal studies, and produced cognitive enhancing effects without prominent stimulant effects at relatively low levels of receptor occupancy, and pronounced wakefulness at higher doses.It has therefore been proposed as a potential treatment for sleep disorders such as narcolepsy and to improve vigilance in old age, particularly in the treatment of conditions such as Alzheimer's disease.It also potentiated the effects of antipsychotic drugs, and has been suggested as an adjuvant treatment for schizophrenia.
Pathways Neuro Signaling Pathway GPCR/G Protein 
Targets Histamine Receptor 

Structure

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