Plinabulin

  • Chemical Properties
CAS No. 714272-27-2 Cat. No. BCP02849
Name Plinabulin
Synonyms NPI-2358;NPI 2358;NPI2358;
Formula C19H20N4O2 M. Wt 336.39
  • Biological Activity
Description NPI-2358 binds to the colchicine-binding site of tubulin. NPI-2358 has potent in-vitro anti-tumor activity against various human tumor cell lines and maintains activity against tumor cell lines with various MDR profiles
Pathways Angiogenesis/Protein Tyrosine Kinase 
Targets VDA 

Structure

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